"Sick as sh*t" is the official medical term to describe a complicated patient with several active issues. It is a term that can only be learned through years and years of medical education and training.
Example of Dialogue
Doctor: So what can you tell me about the patient?
Resident: He's sick as sh*t.
Doctor: You're an incredibly sharp resident! You've impressed me. You're gonna be chief some day. Well done!
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