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Vital signs can range from normal to totally out of whack, depending on the level of a patient's sandwich depletion. The most important [[Physical Exam|physical exam]] findings include:
* ''Point-in-mouth sign'': patient - Patient points finger into mouth as if wanting to eat something* ''Tummy rub sign'': patient - Patient rubs belly in a pattern resembling a hoagie or muffaletta* ''Sandwich sign'' - patient Patient says "I want a sandwich" or some variation of the phrase ("SANDWICH, NOW!" or "I might die if I don't get a tuna on rye")
There are several studies that can aid in the diagnosis:
*''Serum sandwich levels'': - Helpful though many false positives and false negatives*''Serum sandwich IgG antibodies'': - Lack of antibodies suggest lack of sandwiches*''Abdominal imaging'': an - An abdominal X-ray, CT of the abdomen, and MRI abdomen can help reveal the presence or absence of digested sandwiches.*''Endoscopy'': direct - Direct visualization of a sandwichless stomach or intestinal tract is highly sensitive and specific