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'''''Clinical Microbiology Made Ridiculously Difficult''''' is a long, confusing, vague, and totally unenjoyable approach to clinical microbiology, brimming with long-winded essays, lack of humor, and small font. It has been far less successful than its sister publication [[Clinical Microbiology Made Ridiculously Simple]]. But Dr. Thomas Frieden, Director of the CDC, does point out one thing: "At least this book doesn't use the word p**sy."<ref>[http://gomerblog.com/2016/03/cdc-purulent/ CDC: The Adjective of Pus is “Purulent,” Not “P**sy”]</ref>