COVID-19
COVID-19, also known as the novel coronavirus, was discovered in Wuhan, China in December 2019 and has been a goddamn pain-in-the-ass ever since.
Epidemiology
According to the World Health Organization, Centers for Disease Control and Prevention, and our friend Tim, there are currently more than 35 billion confirmed cases of COVID-19. This speaks to the huge burden of disease considering the Earth's population is less than 8 billion.
The first reports were first reported in first reports by the Chinese Centers for Disease Control and Prevention on December 2019 in the city of Wuhan, China. The first document U.S. case occurred in a 35-year-old patient in Washington State, who returned from Wuhan, on January 20, 2020. For Americans, this is when sh*t started to get real.
In a matter of months, COVID-19 had spread to all continents except Antarctica, suggesting that Antarctica somehow has some partial immunity. The World Health Organization declared that COVID-19 was officially a pandemic, thus becoming the last major medical society to realize this. With the exception of China, Taiwan, and South Korea, measures aimed at containment have largely failed. Bribery has failed. Most nations now are looking at strategies involving mitigation or masturbation, whichever one means "to reduce the severity or spread."
Reports suggest that coronavirus is capable of moving back in time.[1].
Virology
Something about betacoronavirus and angiotensin-converting enzyme 2 (ACE2)?
Symptoms
Symptoms can range from no to yes. The most common include fever, nonproductive cough, shortness of breath. In very rare instances, it can present as a scrotal abscess.
Signs
Don't be fooled: though the documented respiratory rate reads as 16, it is most likely 17. Objective fever supports subjective fevers and hypoxemia supports a patient's complaint of "I'm feeling hypoxemic." Chest X-ray is an important diagnostic tool. If Radiology recommends clinical correlation, please defriend them.
Differential Diagnosis
- Upper GI bleed
- Lower GI bleed
- Diabetic foot ulcer
Diagnosis
Diagnosis is best achieved through diagnostic kits, whose status is currently listed as "theoretical" in the United States despite being 3 months into the pandemic. With the eventual coordination of U.S. private and public sectors, over 1 million flawed kits are expected to be available by the end of March 2020. The optimal specimen is an upper respiratory tract sample obtained via nasopharyngeal swab. The U.S. has had difficulty obtaining appropriate specimens, though this is largely attributable to frontline OB/GYNs collecting samples from the vagina and not the nasopharynx.[2]
Treatments
Treatment is largely supportive as there are no known treatments for COVID-19. Interventions such as prayer, screaming "WHY GOD WHY?!" and remdesivir are currently going. A study involving Kaletra (lopinavir/ritonavir) produced disappointment results, as did the ones that looked at sodium barb and precordial thumps. There was controversy when French health minister, Olivier Véran, warned that NSAIDs should be avoided In patients with confirmed COVID-19. This recommended has not been implemented in the United States due to large opposition of military health care professionals who state that eliminating NSAIDs essentially eliminates all that a military health care professional can offer.
References