Benadryl (Diphenhydramine)

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Benadryl (diphenhydramine) is a first-generation antihistamine that should never be given PO and only be given IV in high doses and quickly, especially if a patient asks for it because life is making him or her itchy.[1] Even Nick Saban uses it to treat healthy scratches.[2]

Closely Related Topics


  1. Patients Love New Turkey Sandwich with Dilaudid & Benadryl: The Turlaudidryl Special
  2. Nick Saban Okays IV Benadryl to Treat Tonight’s Healthy Scratches (Gomerblog)

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