The O Sign
From Gomerpedia
Fats said, "These are classic signs: the O sign on the left and the Q sign on the right. The O sign is reversible, but once they get to the Q sign, they never come back." - The House of God
First described in Samuel Shem's The House of God, the O sign refers to the patient's mouth lying with his or her mouth wide open. Though the O sign conveys a poor prognosis, it is treatable.
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